| Title | Season | Episode # | First Aired |
|---|---|---|---|
| North by North Quahog | 4 | 1 | Sunday May 1, 2005 |
| Fast Times at Buddy Cianci Jr. High | 4 | 2 | Sunday May 8, 2005 |
| Blind Ambition | 4 | 3 | Sunday May 15, 2005 |
| Don't Make Me Over | 4 | 4 | Sunday June 5, 2005 |
| The Cleveland-Loretta Quagmire | 4 | 5 | Sunday June 12, 2005 |
| Petarded | 4 | 6 | Sunday June 19, 2005 |
| Brian the Bachelor | 4 | 7 | Sunday June 26, 2005 |
| 8 Simple Rules for Buying My Teenage Daughter | 4 | 8 | Sunday July 10, 2005 |
| Breaking Out Is Hard to Do | 4 | 9 | Sunday July 17, 2005 |
| Model Misbehavior | 4 | 10 | Sunday July 24, 2005 |
| Peter's Got Woods | 4 | 11 | Sunday September 11, 2005 |
| Perfect Castaway | 4 | 12 | Sunday September 18, 2005 |
| Jungle Love | 4 | 13 | Sunday September 25, 2005 |
| PTV | 4 | 14 | Sunday November 6, 2005 |
| Brian Goes Back to College | 4 | 15 | Sunday November 13, 2005 |
| The Courtship of Stewie's Father | 4 | 16 | Sunday November 20, 2005 |
| The Fat Guy Strangler | 4 | 17 | Sunday November 27, 2005 |
| The Father, The Son, and The Holy Fonz | 4 | 18 | Sunday December 18, 2005 |
| Brian Sings | 4 | 19 | Sunday January 8, 2006 |
| Patriot Games | 4 | 20 | Sunday January 29, 2006 |
| I Take Thee Quagmire | 4 | 21 | Sunday March 12, 2006 |
| Sibling Rivalry | 4 | 22 | Sunday March 26, 2006 |
| Deep Throats | 4 | 23 | Sunday April 9, 2006 |
| Peterotica | 4 | 24 | Sunday April 23, 2006 |
| You May Now Kiss The...Uh...Guy Who Receives | 4 | 25 | Sunday April 30, 2006 |
| Petergeist | 4 | 26 | Sunday May 7, 2006 |
| Untitled Griffin Family History | 4 | 27 | Sunday May 14, 2006 |
| Stewie B. Goode (1) | 4 | 28 | Sunday May 21, 2006 |
| Bango Was His Name Oh (2) | 4 | 29 | Sunday May 21, 2006 |
| Stu and Stewie's Excellent Adventure (3) | 4 | 30 | May 21, 2006 |